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Updated: Jul 18, 2025
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Factors associated with in-hospital recurrence of intestinal intussusception in children
Jing Zhang1, Qi Dong2, Xiaoxia Su1
1Department of General Surgery, Hainan Women and Children's Medical Center, Haikou, 570100, China.
Insights
In pediatric patients, children over 1 year old, those with secondary intussusception, and those with enlarged mesenteric lymph nodes have a higher risk of in-hospital recurrence of intestinal intussusception after air enema reduction.
Area of Science:
- Pediatric Gastroenterology
- Surgical Pediatrics
- Medical Diagnostics
Background:
- Intestinal intussusception is a common surgical emergency in infants and young children.
- A subset of patients experience recurrence of intussusception after initial treatment.
- Understanding recurrence factors is crucial for optimizing patient management and outcomes.
Purpose of the Study:
- To identify clinical and demographic factors associated with in-hospital recurrence of intestinal intussusception in pediatric patients.
- To analyze the risk factors for recurrence following air enema reduction.
- To inform clinical practice and improve care for children with intussusception.
Main Methods:
- Retrospective analysis of 624 pediatric patients (aged 0-18 years) treated for intestinal intussusception.
- Data collection included demographic and clinical characteristics from January 2019 to December 2019.
- Logistic regression analysis was employed to determine factors associated with in-hospital recurrence.
Main Results:
- Overall, 11.7% of children experienced in-hospital recurrence after successful air enema reduction.
- Children older than 1 year (OR: 7.65) were at significantly higher risk.
- Secondary intussusception (OR: 14.40) and mesenteric lymph node enlargement (OR: 1.90) were also independently associated with recurrence.
Conclusions:
- Age over 1 year, secondary intussusception, and mesenteric lymph node enlargement are significant predictors of in-hospital recurrence.
- These findings highlight specific patient subgroups requiring closer monitoring post-reduction.
- Identifying these risk factors can aid in developing targeted prevention and management strategies.
Background:
A minority of children experience in-hospital recurrence of intestinal intussusception after treatment. This study investigated the factors associated with in-hospital recurrence of intussusception in pediatric patients in China.
Methods:
This retrospective study included patients aged 0-18 years-old with intestinal intussusception treated at Hainan Women and Children's Medical Center between January 2019 and December 2019. Demographic and clinical characteristics were extracted from the medical records. Factors associated with in-hospital recurrence of intussusception were identified by logistic regression analysis.
Results:
The analysis included 624 children (400 boys) with a median age of 1.8 years (range, 2 months and 6 days to 9 years). Seventy-three children (11.7%) had in-hospital recurrence of intussusception after successful reduction with air enema. Multivariate logistic regression analysis identified age > 1 year-old (odds ratio [OR]: 7.65; 95% confidence interval [95%CI]: 2.70-21.71; P < 0.001), secondary intestinal intussusception (OR: 14.40; 95%CI: 4.31-48.14; P < 0.001) and mesenteric lymph node enlargement (OR: 1.90; 95%CI: 1.13-3.18; P = 0.015) as factors independently associated with in-hospital recurrence of intussusception.
Conclusions:
Age > 1 year-old, secondary intussusception and mesenteric lymph node enlargement were independently associated with increased odds of in-hospital recurrence of intussusception after successful reduction with air enema.
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