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Related Experiment Video

Updated: Jul 18, 2025

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Pseudo-Lyre Sign.

Sonika Kanotra1, Preeti Sharma1, Subhash Bhardwaj2

  • 1Department of E.N.T, Head and Neck Surgery, Govt. Medical College and S.M.G.S. Hospital, Jammu, J&K 180001 India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|August 28, 2023
PubMed
Summary
This summary is machine-generated.

The Pseudo-Lyre sign, often mistaken for carotid body tumors, can be caused by other neck tumors like neurofibroma. This case highlights the importance of considering neurogenic tumors in diagnosing this radiological sign.

Keywords:
Cervical sympathetic chainHorner's syndromeLyre signNeurofibroma

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Area of Science:

  • Radiology
  • Oncology
  • Neurosurgery

Background:

  • The Lyre sign on radiological imaging typically suggests a carotid body tumor.
  • However, other cervical tumors can mimic this sign, leading to diagnostic challenges.

Purpose of the Study:

  • To investigate the causes of the Pseudo-Lyre sign, which appears in tumors other than carotid body tumors.
  • To report a rare case of cervical sympathetic chain neurofibroma presenting with the Pseudo-Lyre sign.

Main Methods:

  • Case report of a 34-year-old female with a pulsatile mass in the carotid triangle.
  • Radiological investigation including imaging to assess arterial splaying.
  • Surgical excision and histopathological confirmation of the tumor.

Main Results:

  • Radiological findings suggested a carotid body tumor due to the Lyre sign (arterial splaying).
  • Surgery revealed a neurofibroma originating from the cervical sympathetic chain (CSC).
  • Histopathology confirmed the diagnosis of neurofibroma.

Conclusions:

  • This case is the first reported instance of a cervical sympathetic chain neurofibroma causing the Pseudo-Lyre sign.
  • The Pseudo-Lyre sign can be indicative of neurogenic tumors, not exclusively carotid body tumors.
  • Preoperative diagnostic confirmation is crucial for masses presenting with the Pseudo-Lyre sign.