Relationship Between Rhinitis, Nasal Obstruction and Hypothyroidism: A Follow Up Study with Pre-post Treatment with...

Area of Science:

• Endocrinology
• Otorhinolaryngology
• Internal Medicine

Background:

• Hypothyroidism is a prevalent thyroid disorder in India.
• Rhinitis and nasal obstruction are common ENT complaints.
• Existing research suggests a link between hypothyroidism and these nasal symptoms.

Purpose of the Study:

• To evaluate the effectiveness of levothyroxine treatment on rhinitis and nasal obstruction symptoms in hypothyroid patients.
• To assess changes in nasal obstruction symptom scores and nasal airflow after treatment.

Main Methods:

• 50 patients with hypothyroidism, rhinitis, and nasal obstruction were enrolled.
• Nasal Obstruction Symptom Evaluation (NOSE) scores and Peak Nasal Inspiratory Flow (PNIF) rates were recorded.
• Patients received levothyroxine treatment, with follow-ups at 1 and 3 months.

Main Results:

• Levothyroxine treatment led to significant improvements in TSH levels, NOSE scores, and PNIF rates (P < 0.001).
• Symptom improvement was most pronounced in the 15-50 age group (88%).
• A significant association was confirmed between hypothyroid status and rhinitis with nasal obstruction.

Conclusions:

• Levothyroxine is effective in improving rhinitis and nasal obstruction symptoms in patients with hypothyroidism.
• The study reinforces the association between thyroid dysfunction and upper airway symptoms.
• Early diagnosis and treatment of hypothyroidism may alleviate nasal complaints.