Electrochemical Biosensors Based on Enzyme Inhibition Effect
Valentyna Arkhypova1, Oleksandr Soldatkin1, Alexei Soldatkin1,2
1Department of Biomolecular Electronics, Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine, 150 Zabolotnogo Str., 03143, Kyiv, Ukraine.
Chemical Record (New York, N.Y.)
|August 28, 2023
Summary
Developed electrochemical biosensors utilizing enzyme inhibition offer rapid environmental toxin detection. These biosensors complement traditional methods, providing early warnings and aiding in emergency response decisions.
Area of Science:
- Environmental Science
- Analytical Chemistry
- Biotechnology
Background:
- Electrochemical biosensors are crucial for detecting environmental contaminants.
- Enzyme inhibition-based biosensors offer a promising approach for rapid analysis.
- Existing methods for toxin detection can be time-consuming and costly.
Purpose of the Study:
- To design and investigate laboratory prototypes of electrochemical biosensors based on enzyme inhibition.
- To evaluate the advantages and disadvantages of these enzyme inhibition biosensors.
- To position these biosensors as complementary tools to traditional analytical methods for environmental monitoring.
Main Methods:
- Design and laboratory prototyping of electrochemical biosensors.
- Investigation of enzyme inhibition effects for sensing applications.
- Assessment of biosensor performance and suitability for large-scale production.
Main Results:
- Successful design and investigation of electrochemical biosensor prototypes.
- Demonstration of suitability for large-scale production technologies.
- Discussion of the benefits and drawbacks of the developed enzyme inhibition biosensors.
Conclusions:
- Electrochemical biosensors based on enzyme inhibition are viable tools for environmental monitoring.
- These biosensors serve as effective early warning systems for toxic substances.
- The developed biosensors complement traditional methods, offering cost and time savings in emergencies.
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