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Updated: Jul 17, 2025

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
POLYPOIDAL CHOROIDAL VASCULOPATHY ASSOCIATED WITH SECTOR RETINITIS PIGMENTOSA.
Ramya Appanraj1, George J Manayath, Shishir Verghese
1Department of Retina and Vitreous Services, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, India.
Polypoidal choroidal vasculopathy can occur with sector retinitis pigmentosa, even with thin choroids. Multimodal imaging is crucial for distinguishing this condition from Type-1 macular neovascularization.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Choroidal Vasculopathy
Background:
- Sector retinitis pigmentosa (RP) is a genetic retinal disorder.
- Polypoidal choroidal vasculopathy (PCV) is a pachychoroid vascular condition.
Observation:
- A 63-year-old woman presented with progressive vision loss in her left eye.
- Fundus examination and multimodal imaging revealed sector RP in both eyes and active extramacular PCV in the left eye.
- Choroidal thinning was noted in both eyes via spectral-domain optical coherence tomography (SD-OCT).
Findings:
- The patient received an intravitreal bevacizumab injection in the left eye.
- One month post-treatment, visual acuity in the left eye remained stable.
- SD-OCT confirmed reduced subretinal fluid and polypoidal lesion size.
Implications:
- PCV may be associated with RP, particularly in cases with thin choroids.
- Multimodal imaging is essential for differentiating PCV from Type-1 macular neovascularization.
- This case highlights the importance of comprehensive imaging in complex retinal cases.
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