Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis.

Nature·2025
Same author

Author Correction: 3C methods in cancer research: recent advances and future prospects.

Experimental & molecular medicine·2024
Same author

5'-tRNA<sup>Gly(GCC)</sup> halves generated by IRE1α are linked to the ER stress response.

Nature communications·2024
Same author

Temporally distinct 3D multi-omic dynamics in the developing human brain.

Nature·2024
Same author

Applications of Single-Cell Omics Technologies for Induced Pluripotent Stem Cell-Based Cardiovascular Research.

International journal of stem cells·2024
Same author

3C methods in cancer research: recent advances and future prospects.

Experimental & molecular medicine·2024

Related Experiment Video

Updated: Jun 17, 2026

In vitro and in vivo Bioluminescence Reporter Gene Imaging of Human Embryonic Stem Cells
12:19

In vitro and in vivo Bioluminescence Reporter Gene Imaging of Human Embryonic Stem Cells

Published on: May 2, 2008

21.9K

In Vivo Stem Cell Imaging Principles and Applications.

Seongje Hong1, Dong-Sung Lee2, Geun-Woo Bae1

  • 1Department of Anatomy, College of Medicine, Chung-Ang University, Seoul, Korea.

International Journal of Stem Cells
|August 29, 2023
PubMed
Summary

Stem cell research utilizes molecular imaging to track transplanted cells. This review explores advanced in vivo imaging techniques essential for evaluating stem cell therapies in regenerative medicine.

Keywords:
Magnetic resonance imagingOptical imagingPositron emission tomographySingle-photon emission computed tomographyStem cellsin vivo molecular imaging

More Related Videos

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice
10:25

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice

Published on: June 13, 2012

11.2K
Development, Expansion, and In vivo Monitoring of Human NK Cells from Human Embryonic Stem Cells hESCs and Induced Pluripotent Stem Cells iPSCs
09:02

Development, Expansion, and In vivo Monitoring of Human NK Cells from Human Embryonic Stem Cells hESCs and Induced Pluripotent Stem Cells iPSCs

Published on: April 23, 2013

16.9K

Related Experiment Videos

Last Updated: Jun 17, 2026

In vitro and in vivo Bioluminescence Reporter Gene Imaging of Human Embryonic Stem Cells
12:19

In vitro and in vivo Bioluminescence Reporter Gene Imaging of Human Embryonic Stem Cells

Published on: May 2, 2008

21.9K
Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice
10:25

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice

Published on: June 13, 2012

11.2K
Development, Expansion, and In vivo Monitoring of Human NK Cells from Human Embryonic Stem Cells hESCs and Induced Pluripotent Stem Cells iPSCs
09:02

Development, Expansion, and In vivo Monitoring of Human NK Cells from Human Embryonic Stem Cells hESCs and Induced Pluripotent Stem Cells iPSCs

Published on: April 23, 2013

16.9K

Area of Science:

  • Regenerative Medicine
  • Molecular Imaging
  • Stem Cell Biology

Background:

  • Stem cells are crucial for tissue regeneration and treating congenital defects.
  • Various stem cell types, including induced pluripotent stem cells (iPSCs), embryonic stem cells (ESCs), mesenchymal stem cells (MSCs), and neuroprogenitor stem cells (NSCs), are investigated for cell-based therapeutics.
  • Successful stem cell transplantation requires evaluating cell origin, administration route, in vivo biodistribution, survival, function, and mobility.

Purpose of the Study:

  • To review the principles and recent advances in in vivo molecular imaging for stem cell research.
  • To highlight the importance of imaging for assessing the efficacy and safety of stem cell therapies.

Main Methods:

  • Discussion of various molecular imaging modalities used for in vivo stem cell tracking.
  • Overview of techniques including optical imaging, magnetic resonance imaging (MRI), ultrasound (US), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).

Main Results:

  • Molecular imaging enables non-invasive monitoring of transplanted stem cells within a living organism.
  • Different imaging modalities offer unique advantages for visualizing stem cell behavior and distribution.
  • Advances in imaging are critical for the clinical translation of stem cell therapies.

Conclusions:

  • In vivo molecular imaging is indispensable for advancing stem cell research and regenerative medicine.
  • Continued development of imaging technologies will improve the evaluation and application of stem cell-based treatments.
  • Understanding stem cell dynamics through imaging is key to realizing their therapeutic potential.