Related Experiment Video
Updated: Jul 17, 2025

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
Published on: December 23, 2022
EspE3 plays a role in the pathogenicity of avian pathogenic Escherichia coli
Qianwen Li1,2,3,4,5, Zhao Qi6,7, Dandan Fu6,7
1Anhui Province Key Laboratory of Veterinary and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China. 1061114200@qq.com.
Abstract:
APEC encodes multiple virulence factors that have complex pathogenic mechanisms. In this study, we report a virulence factor named EspE3, which can be secreted from APEC. This protein was predicted to have a leucine-rich repeat domain (LRR) and may have a similar function to IpaH class effectors of the type III secretion system (T3SS). For further exploration, the regulatory correlation between the espE3 and ETT2 genes in APEC was analysed. We then assessed the pathogenicity of EspE3, detected it in APEC secretion proteins and screened the proteins of EspE3 that interact with chicken trachea epithelial cells. This study provides data on a new virulence factor for further exploring the pathogenic mechanism of APEC.
More Related Videos
Related Concept Videos
Chemotaxis in E. coli
Stringent Response in E. coli
Viral Replication: Lytic Cycle
Gram-negative Bacterial Protein Secretion Systems

