[Clinical aspects and diagnosis of diffuse eosinophilic fasciitis]

The authors presented an analysis of 10 cases of eosinophilic fasciitis (EF): 6 men and 4 women aged 18 to 55. In 4 patients the disease followed excessive physical exercise. Pronounced induration of the limb tissues with the development of flexion contractures, hypereosinophilia prevailed in the clinical picture of the disease, morphology showed a picture of fasciitis. A positive time course was noted in the presence of corticosteroid therapy which in 2 patients was combined with azathioprine and carbohemoperfusion. Besides, there was a patient with the combination of the classical signs of scleredema and EF. EF appears to be a nosological entity. The probability of combined forms requires a further study.