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Idiopathic eosinophilic cholecystitis with cholelithiasis: Two rare cases report
Moatasem Hussein Al-Janabi1, Bayan Youssef Alsayed Hussein2, Julia Nehad Kahwaji2
1Department of Pathology, Cancer Research Center, Tishreen University Hospital, Latakia, Syria.
International Journal of Surgery Case Reports
|August 30, 2023
Summary
Eosinophilic cholecystitis is a rare gallbladder condition with over 90% eosinophil infiltration. Diagnosis requires histopathology, with cholecystectomy as the definitive treatment.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Eosinophilic cholecystitis is a rare gallbladder disease, accounting for 0.25-6.4% of cholecystitis cases.
- Its pathogenesis remains largely unknown, though associations with hypereosinophilic syndrome, infections, and certain drugs exist.
Observation:
- This study presents two cases of eosinophilic cholecystitis.
- A 27-year-old female and a 30-year-old male presented with symptoms of acute and chronic cholecystitis, respectively.
- Ultrasound indicated calculous cholecystitis in both patients, leading to cholecystectomy.
Findings:
- Histopathological examination of surgical specimens confirmed eosinophilic cholecystitis.
- The condition is characterized by significant eosinophil infiltration in the gallbladder wall's lamina propria and muscle layers.
Implications:
- Histopathological investigation is crucial for diagnosing eosinophilic cholecystitis, as clinical presentation is typically non-specific.
- Cholecystectomy is the definitive treatment, and a thorough assessment for underlying causes is recommended for affected patients.
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