Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Pituitary adenomas extending into the orbit].

S K Akshulakov, N K Serova

    Zhurnal Voprosy Neirokhirurgii Imeni N. N. Burdenko
    |July 1, 1986
    PubMed
    Summary

    Giant pituitary adenomas can invade the orbit via the cavernous sinus, affecting vision and eye movement. This study highlights key neuro-ophthalmological signs indicating tumor spread in patients with hormonally active pituitary adenomas.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Surgical treatment of orbitocranial and orbital cavernous venous malformations (ophthalmological aspects)].

    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko·2025
    Same author

    [Growing skull fracture of the orbital roof: case report and literature review].

    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko·2024
    Same author

    [Use of optical coherence tomography in diagnosis of retinal lymphomas].

    Vestnik oftalmologii·2022
    Same author

    [Results of radiation therapy for optic nerve sheath meningioma].

    Vestnik oftalmologii·2022
    Same author

    [Hypofractionated stereotactic irradiation for optic nerve glioma].

    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko·2022
    Same author

    [Papilledema as a sign of intracranial hypertension].

    Vestnik oftalmologii·2022

    Area of Science:

    • Neurosurgery
    • Endocrinology
    • Ophthalmology

    Background:

    • Giant pituitary adenomas are rare tumors with potential for significant local invasion.
    • Invasion of the orbit by pituitary adenomas can lead to complex neuro-ophthalmological symptoms.

    Purpose of the Study:

    • To investigate the pattern of orbital invasion by giant pituitary adenomas.
    • To identify characteristic neuro-ophthalmological findings associated with orbital invasion.
    • To correlate clinical findings with tumor spread using diagnostic imaging.

    Main Methods:

    • Retrospective analysis of 35 patients with giant pituitary adenomas.
    • Detailed review of neuro-ophthalmological examinations.
    • Correlation of clinical data with radiological findings (X-ray diagnosis).

    Main Results:

    • Orbital invasion through the superior orbital suture from the cavernous sinus occurred in 5 of 35 patients.
    • All 5 patients with orbital invasion had hormonally active pituitary adenomas.
    • Common findings included marked chiasmal syndrome, mild exophthalmos, and oculomotor disorders.

    Conclusions:

    • Giant pituitary adenomas, particularly hormonally active ones, can invade the orbit.
    • Specific neuro-ophthalmological signs are indicative of tumor spread into the orbit.
    • X-ray diagnosis aids in assessing the extent of tumor invasion.

    Related Experiment Videos