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Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
Published on: February 23, 2024
Multidisciplinary treatment for acute massive upper gastrointestinal bleeding secondary to post-burn stress in a
Yangping Wang1, Yong Yang2, Ziqin Shu1
1State Key Laboratory of Trauma, Burn and Combined Injury, Institute of Burn Research, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Insights
Severe burns can cause dangerous gastrointestinal bleeding in children. A combination of gastroscopy and embolization successfully treated a pediatric patient with severe post-burn bleeding, offering a valuable clinical reference.
Area of Science:
- Gastroenterology
- Pediatric Surgery
- Interventional Radiology
Background:
- Severe burns can lead to gastric and duodenal erosions and ulcers, potentially causing life-threatening hemorrhage.
- Current treatments for post-burn gastrointestinal hemorrhage include medication and endoscopy, but combined approaches are uncommon.
- Massive upper gastrointestinal bleeding in pediatric burn patients is a rare but critical complication.
Background:
Severe burns can readily induce gastric and duodenal mucosal erosions and superficial ulcers. In severe cases, haemorrhage or perforation of peptic ulcers might occur, threatening the lives of patients. At present, gastrointestinal haemorrhage after burns is treated mainly with drugs and gastrointestinal endoscopy. However, multidisciplinary treatment of gastroscopy combined with vascular embolization is rare.
Case:
A boy aged 3 years and 4 months was admitted to the hospital, scalded by boiling water on multiple parts of the body. On the 8th day after the injury, the patient continuously produced a large amount of tarry black stool, and the faecal occult blood test was positive. Haemostatic drug treatment was ineffective, and severe shock and disseminated intravascular coagulation (DIC) occurred. Under the guidance of a multidisciplinary team (MDT), a gastroscopy examination was performed and showed bleeding from a duodenal bulb ulcer. Due to a small intestinal lumen and thin intestinal wall, bleeding could not be controlled by gastroscopy. However, the bleeding point was clarified by gastroscopy and then gastroduodenal artery embolization was performed efficiently. No active gastrointestinal bleeding was observed after the surgery. The patient was followed for 6 months after discharge, and no gastrointestinal haemorrhage recurred.
Conclusions:
This is a rare case of acute massive upper gastrointestinal bleeding secondary to post-burn stress in paediatric patients. For paediatric patients who cannot be treated by endoscopy, transcatheter embolization may be safer and more effective for achieving haemostasis. Through the collaboration of the MDT, gastroscopy combined with interventional embolization was performed, which successfully stopped the massive bleeding and saved the child`s life, making it worthy of clinical reference.
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