Related Experiment Video
Updated: Jul 17, 2025

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Explaining Obesity- and Smoking-related Healthcare Costs through Unconditional Quantile Regression
Bijan Borah1, James Naessens1, Kerry Olsen2
1Mayo Clinic, Health Care Policy and Research Division, College of Medicine, Rochester, MN, USA.
Abstract:
Background: This paper assesses obesity- and smoking-related incremental healthcare costs for the employees and dependents of a large U.S. employer. Objectives: Unlike previous studies, this study evaluates the distributional effects of obesity and smoking on healthcare cost distribution using a recently developed econometric framework: the unconditional quantile regression (UQR). Methods: Results were compared with the traditional conditional quantile regression (CQR), and the generalized linear modeling (GLM) framework that is commonly used for modeling healthcare cost. Results: The study found strong evidence of association of healthcare costs with obesity and smoking. More importantly, the study found that these effects are substantially higher in the upper quantiles of the healthcare cost distribution than in the lower quantiles. The insights on the heterogeneity of impacts of obesity and smoking on healthcare costs would not have been captured by traditional mean-based approaches. The study also found that UQR impact estimates were substantially different from CQR impact estimates in the upper quantiles of the cost distribution. Conclusions: These results suggest the potential role that smoking cessation and weight management programs can play in arresting the growth in healthcare costs. Specifically, given the finding that obesity and smoking have markedly higher impacts on high-cost patients, such programs appear to have significant cost saving potential if targeted toward high-cost patients.
More Related Videos
Related Concept Videos
Statistical Methods for Analyzing Epidemiological Data
Obesity
Stress Prevention and Stress Management Techniques IV
Bias in Epidemiological Studies
Causality in Epidemiology
Regression Toward the Mean

