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Updated: Jul 17, 2025

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
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Metal-free thiolation of sulfonyl hydrazone with thiophenol: synthesis of 4-thio-chroman and diarylmethyl thioethers

Kasim Ali1,2, Indranil Chatterjee1, Gautam Panda1,2

  • 1Medicinal & Process Chemistry Division CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Lucknow 226031, India. gautam_panda@cdri.res.in.

Organic & Biomolecular Chemistry
|September 5, 2023
PubMed

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Thiols and sulfides are sulfur analogs of alcohols and ethers, respectively, where the sulfur atom takes the place of the oxygen atom. Thus, thiols are generally represented as RSH, where R is an alkyl substituent and —SH is the functional group. On the other hand, in sulfides, the central sulfur atom is bonded to two hydrocarbon groups on either side. Depending upon the type of group, sulfides can be either symmetrical or asymmetrical. Both thiols and sulfides display a bent geometry,...
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