Related Experiment Video
Updated: Jul 17, 2025

A Practical Guide to Phylogenetics for Nonexperts
Published on: February 5, 2014
Sequence Alignment/Map format: a comprehensive review of approaches and applications
Yuansheng Liu1, Xiangzhen Shen1, Yongshun Gong2
1College of Computer Science and Electronic Engineering, Hunan University, 410086, Changsha, China.
Abstract:
The Sequence Alignment/Map (SAM) format file is the text file used to record alignment information. Alignment is the core of sequencing analysis, and downstream tasks accept mapping results for further processing. Given the rapid development of the sequencing industry today, a comprehensive understanding of the SAM format and related tools is necessary to meet the challenges of data processing and analysis. This paper is devoted to retrieving knowledge in the broad field of SAM. First, the format of SAM is introduced to understand the overall process of the sequencing analysis. Then, existing work is systematically classified in accordance with generation, compression and application, and the involved SAM tools are specifically mined. Lastly, a summary and some thoughts on future directions are provided.
More Related Videos
Related Concept Videos
Evolutionary Relationships through Genome Comparisons
Modern Molecular Taxonomy
Multi-species Conserved Sequences
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
Genome Annotation and Assembly

