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Updated: Aug 6, 2026

Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
10:42

Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

Published on: January 3, 2018

Stability of o-phthalaldehyde-derived isoindoles

W A Jacobs, M W Leburg, E J Madaj

    Analytical Biochemistry
    |August 1, 1986
    PubMed
    Summary

    The stability of 1-alkylthio-2-alkylisoindoles, used in precolumn derivatization, depends on reaction conditions. Minimizing excess o-phthalaldehyde is key to preventing isoindole degradation and ensuring derivative stability.

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