Related Experiment Video
Updated: Jul 17, 2025

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
Published on: August 11, 2016
[A case of congenital grouped albinotic spots]
1Center of Ophthalmology,the Second Affiliated Hospital of Nanchang University,Nanchang 330008,China.
Abstract:
This case report presents a 5-year-old male child with a complaint of poor vision in the left eye for the past 2 years, who sought ophthalmic evaluation. There was no apparent systemic pigment loss, but multiple small, flat, and well-defined white lesions were observed in the retinal pigment epithelium of the left eye. Autofluorescence imaging of the fundus revealed widespread patchy hyperautofluorescence corresponding to the lesions. Fluorescein angiography demonstrated early and stable hyperfluorescence without leakage in these spots. Optical coherence tomography examination revealed thickening and material accumulation in the ellipsoid zone that corresponded to the lesions. Based on clinical findings, the diagnosis of congenital grouped albinotic spots was established.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Genetic Lingo
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

