Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

13.4K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
13.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Midazolam premedication: shaping pediatric perioperative outcomes.

Journal of anesthesia·2026
Same author

Harnessing dual gradients of topography and mineralization via a modified electrospinning strategy in polyacrylonitrile/MWCNT nanofibrous membranes for enhanced osteogenic differentiation.

Biomedical materials (Bristol, England)·2026
Same author

Incidence and Epidemiologic Characteristics of Measles in the Republic of Korea Following Elimination Verification (2014-2025).

Public health weekly report·2026
Same author

The psychological health of forensic investigators following mass fatality incidents: a cross-sectional study 9 months after the Jeju Air crash in South Korea.

Frontiers in public health·2026
Same author

Clinical Diagnoses After Positive Cognitive Screening: A Case Series of Older Surgical Patients.

A&A practice·2026
Same author

Insights into Native Single-Atom Electrocatalyst Site Structures.

ACS nano·2026

Related Experiment Video

Updated: Jul 17, 2025

How to Build a Laser Speckle Contrast Imaging LSCI System to Monitor Blood Flow
05:24

How to Build a Laser Speckle Contrast Imaging LSCI System to Monitor Blood Flow

Published on: November 11, 2010

23.8K

Projection mapping system for laser speckle contrast image: feasibility study for clinical application.

Subin Park1, Insun Yeum1, Donghwan Ko1

  • 1Yonsei University, Department of Biomedical Engineering, Wonju-Si, Republic of Korea.

Journal of Biomedical Optics
|September 6, 2023
PubMed
Summary

This study introduces a projection mapping system for laser speckle contrast images (LSCIs) to directly visualize blood flow in the region of interest, overcoming spatial mismatch issues and demonstrating clinical feasibility.

Keywords:
blood flow monitoringlaser speckle contrast imageprojection mappingprojector

More Related Videos

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation
07:20

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation

Published on: August 30, 2017

8.5K
High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques
11:34

High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques

Published on: December 3, 2013

15.7K

Related Experiment Videos

Last Updated: Jul 17, 2025

How to Build a Laser Speckle Contrast Imaging LSCI System to Monitor Blood Flow
05:24

How to Build a Laser Speckle Contrast Imaging LSCI System to Monitor Blood Flow

Published on: November 11, 2010

23.8K
A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation
07:20

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation

Published on: August 30, 2017

8.5K
High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques
11:34

High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques

Published on: December 3, 2013

15.7K

Area of Science:

  • Biomedical Optics
  • Medical Imaging

Background:

  • Laser speckle contrast imaging (LSCI) monitors blood flow perfusion.
  • Conventional LSCI observation on monitors can cause spatial mismatch with the imaging region of interest (IROI).

Purpose of the Study:

  • To develop and evaluate a projection mapping (PM) system for LSCIs (PMS_LSCI).
  • To enable direct observation of blood flow perfusion within the IROI by projecting LSCIs.

Main Methods:

  • The PMS_LSCI integrates a camera, optics, laser projector, and GUI software.
  • Spatial matching was achieved by adjusting software and validated through in vitro and in vivo studies.
  • Feasibility of real-time PM for LSCI was assessed in vivo.

Main Results:

  • Spatial mismatch ranged from 2.74% to 6.47% based on surface curvature.
  • The PMS_LSCI achieved real-time projection of LSCI across four distinct blood flow states.
  • The system demonstrated clinical feasibility in both in vitro and in vivo settings.

Conclusions:

  • The PMS_LSCI projects LSCI directly onto the IROI using a projector, eliminating monitor-based spatial mismatch.
  • The developed system shows significant clinical potential for enhanced blood flow monitoring.