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Collateral grading systems in retrograde percutaneous coronary intervention of chronic total occlusions
Yvemarie B O Somsen1, Ruben W de Winter1, Rocco Giunta2
1Departments of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Insights
The Japanese Channel (J-Channel) score shows promise for guiding retrograde percutaneous coronary intervention (PCI) in chronic total occlusions (CTOs). However, its ability to predict overall technical success in CTO PCI is limited, similar to other collateral grading systems.
Area of Science:
- Cardiovascular Interventions
- Interventional Cardiology
- Coronary Artery Disease
Background:
- The Japanese Channel (J-Channel) score was developed to assist in retrograde percutaneous coronary intervention (PCI) for chronic total coronary occlusions (CTOs).
- The predictive capabilities of the J-Channel score have not been compared against established collateral grading systems like the Rentrop classification and Werner grade.
Purpose of the Study:
- To evaluate the predictive value of the J-Channel score, Rentrop classification, and Werner grade.
- To assess their effectiveness in predicting successful collateral channel (CC) guidewire crossing and technical success in CTO PCI.
Main Methods:
- A prospective study involving 600 patients undergoing CTO PCI.
- Collateral grading systems were assessed using dual catheter injection.
- Successful CC guidewire crossing and technical CTO PCI success were defined based on specific criteria.
Main Results:
- The J-Channel score demonstrated predictive value for CC guidewire crossing, comparable to Rentrop classification and superior to Werner grade (AUC 0.743).
- Technical CTO PCI success was achieved in 90% of patients.
- Rentrop classification showed slightly better discrimination for technical success (0.676) than J-Channel (0.664) and Werner grade (0.589).
Conclusions:
- The J-Channel score may assist in selecting collateral channels for retrograde CTO PCI.
- All evaluated grading systems (J-Channel, Rentrop, Werner) have limited predictive value for the technical success of CTO PCI.
Background:
The Japanese Channel (J-Channel) score was introduced to aid in retrograde percutaneous coronary intervention (PCI) of chronic total coronary occlusions (CTOs). The predictive value of the J-Channel score has not been compared with established collateral grading systems such as the Rentrop classification and Werner grade.
Aims:
To investigate the predictive value of the J-Channel score, Rentrop classification and Werner grade for successful collateral channel (CC) guidewire crossing and technical CTO PCI success.
Methods:
A total of 600 prospectively recruited patients underwent CTO PCI. All grading systems were assessed under dual catheter injection. CC guidewire crossing was considered successful if the guidewire reached the distal segment of the CTO vessel through a retrograde approach. Technical CTO PCI success was defined as thrombolysis in myocardial infarction flow grade 3 and residual stenosis <30%.
Results:
Of 600 patients, 257 (43%) underwent CTO PCI through a retrograde approach. Successful CC guidewire crossing was achieved in 208 (81%) patients. The predictive value of the J-Channel score for CC guidewire crossing (area under curve 0.743) was comparable with the Rentrop classification (0.699, p = 0.094) and superior to the Werner grade (0.663, p = 0.002). Technical CTO PCI success was reported in 232 (90%) patients. The Rentrop classification exhibited a numerically higher discriminatory ability (0.676) compared to the J-Channel score (0.664) and Werner grade (0.589).
Conclusions:
The J-channel score might aid in strategic collateral channel selection during retrograde CTO PCI. However, the J-Channel score, Rentrop classification, and Werner grade have limited value in predicting technical CTO PCI success.
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