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Updated: Jul 17, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
Published on: December 29, 2021
How close are we to storing data in DNA?
Joao Henrique Diniz Brandao Gervasio1, Henrique da Costa Oliveira2, Andre Guilherme da Costa Martins2
1Bionanomanufacturing Center, IPT - Institute for Technological Research, Sao Paulo, SP, Brazil; Department of Bioinformatics, UFMG - Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil; Department of Statistics, University of Oxford, Oxford, UK.
Abstract:
DNA is an intelligent data storage medium due to its stability and high density. It has been used by nature for over 3.5 billion years. Compared with traditional methods, DNA offers better compression and physical density. DNA can retain information for thousands of years. However, challenges exist in scalability, standardization, metadata gathering, biocybersecurity, and specialized tools. Addressing these challenges is crucial for widespread implementation. Collaboration among experts, as well as keeping the future in mind, is needed to unlock the full potential of DNA data storage, which promises low energy costs, high-density storage, and long-term stability.
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