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Updated: Jul 17, 2025

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Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
Published on: October 10, 2020
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GLUT5: structure, functions, diseases and potential applications
Aqian Song1, Yuanpeng Mao2, Hongshan Wei1,2
1Department of Gastroenterology, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Acta Biochimica Et Biophysica Sinica
|September 7, 2023
Summary
Glucose transporter 5 (GLUT5) facilitates fructose uptake. This review explores GLUT5
Area of Science:
- Biochemistry and Molecular Biology
- Metabolic Research
- Oncology
Background:
- Dietary fructose intake is increasing, linked to obesity and metabolic disorders.
- Glucose transporter 5 (GLUT5) is crucial for fructose absorption and metabolism.
- GLUT5's role in digestive diseases is established; its link to cancer is emerging.
Conclusions:
- GLUT5 plays a significant role in fructose metabolism and disease development.
- Understanding GLUT5's structure-function relationship is key to its therapeutic potential.
- GLUT5 represents a promising molecular target for novel cancer therapies.
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