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Updated: Jul 22, 2026

Identification of Protein Interacting Partners Using Tandem Affinity Purification
Published on: February 25, 2012
Antiviral Drug Target Identification and Ligand Discovery
Hershna Patel1, Dipankar Sengupta2
1School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK. h.patel28@herts.ac.uk.
Abstract:
This chapter intends to provide a general overview of web-based resources available for antiviral drug discovery studies. First, we explain how the structure for a potential viral protein target can be obtained and then highlight some of the main considerations in preparing for the application of receptor-based molecular docking techniques. Thereafter, we discuss the resources to search for potential drug candidates (ligands) against this target protein receptor, how to screen them, and preparing their analogue library. We make specific reference to free, online, open-source tools and resources which can be applied for antiviral drug discovery studies.
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