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Updated: Jul 17, 2025
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A Hybrid DNA Extraction Method for the Qualitative and Quantitative Assessment of Bacterial Communities from Poultry Production Samples
Published on: December 10, 2014
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RNA sequencing transcriptomics and metabolomics in three poultry breeds
Qidong Zhu1, Yuanli Cai2, Chuanpi Xiao1,3
1Key Laboratory of Efficient Utilization of Nongrain Feed Resources, College of Animal Science and Technology, Shandong Agricultural University, Taian, Shandong, 271018, China.
Scientific Data
|September 7, 2023
Summary
This study analyzed chicken gene expression and metabolites across different breeds. The data provides a valuable resource for understanding poultry genetics and biomedical research.
Area of Science:
- Genomics and Metabolomics in Animal Models
Background:
- Chickens serve as versatile model organisms in biomedical research.
- Understanding genetic and metabolic variations is crucial for advancing poultry research.
Purpose of the Study:
- To perform integrated metabolomic and RNA sequencing (RNA-Seq) transcriptomic analyses on chicken hypothalamus, liver, and serum.
- To provide comprehensive transcriptional and metabolic data for diverse poultry breeds.
Main Methods:
- Utilized high-throughput RNA sequencing (RNA-Seq) for transcriptomic analysis.
- Employed liquid chromatography coupled with mass spectrometry (LC/MS) for metabolomic profiling.
- Analyzed 36 samples from three distinct poultry breeds.
Main Results:
- Generated detailed transcriptomic data for hypothalamus and liver tissue.
- Produced comprehensive metabolomic data for liver tissue and serum.
- Characterized molecular differences across various genetic backgrounds in chickens.
Conclusions:
- The generated datasets offer a valuable resource for poultry biomedical research.
- Facilitates further studies on the genetic and metabolic underpinnings of chicken models.
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