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Updated: Jul 16, 2025

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A mechanistic blueprint for enzymatic reduction by a modular polyketide synthase

Amy E Fraley1

  • 1Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zurich, Switzerland.

Structure (London, England : 1993)
|September 8, 2023
PubMed
Summary

Linker peptides act as hydrophobic glue to organize domains in modular polyketide synthases. This study reveals unique structural features of these modular systems compared to other megasynthases.

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