Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.
Overview of Electron Microscopy01:25

Overview of Electron Microscopy

The wavelengths of visible light ultimately limit the maximum theoretical resolution of images created by light microscopes. Most light microscopes can only magnify 1000X, and a few can magnify up to 1500X. Electrons, like electromagnetic radiation, can behave like waves, but with wavelengths of 0.005 nm, they produce significantly greater resolution up to 0.05 nm as compared to 500 nm for visible light. An electron microscope (EM) can create a sharp image that is magnified up to 2,000,000X.
Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polarity-sensitive dual emissive fluorescent carbon dots as highly specific targeting probes for lipid droplets in live cells.

Nanoscale advances·2025
Same author

Random Lasing for Bimodal Imaging and Detection of Tumor.

Biosensors·2023
Same author

Bessel Beams in Ophthalmology: A Review.

Micromachines·2023
Same author

Ultra-thin light-weight laser-induced-graphene (LIG) diffractive optics.

Light, science & applications·2023
Same author

Raman spectroscopy for viral diagnostics.

Biophysical reviews·2023
Same author

Au nano-urchins enabled localized surface plasmon resonance sensing of beta amyloid fibrillation.

Nanoscale advances·2022

Related Experiment Video

Updated: Jul 3, 2026

Using Microwave and Macroscopic Samples of Dielectric Solids to Study the Photonic Properties of Disordered Photonic Bandgap Materials
10:35

Using Microwave and Macroscopic Samples of Dielectric Solids to Study the Photonic Properties of Disordered Photonic Bandgap Materials

Published on: September 26, 2014

12.3K

Lasing from Micro- and Nano-Scale Photonic Disordered Structures for Biomedical Applications.

R Gayathri1, C S Suchand Sandeep1, C Vijayan2

  • 1Centre for Optical and Laser Engineering, School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore.

Nanomaterials (Basel, Switzerland)
|September 9, 2023
PubMed
Summary

Disordered photonic media enable random lasing through light scattering. Recent advancements show potential for random lasers in biomedical imaging and biosensing applications.

Keywords:
bioimagingbiosensingdisordered photonicsnanomaterialsplasmonicsrandom lasing

More Related Videos

Free-form Light Actuators — Fabrication and Control of Actuation in Microscopic Scale
08:17

Free-form Light Actuators — Fabrication and Control of Actuation in Microscopic Scale

Published on: May 25, 2016

9.3K
Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging
07:14

Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging

Published on: April 11, 2025

627

Related Experiment Videos

Last Updated: Jul 3, 2026

Using Microwave and Macroscopic Samples of Dielectric Solids to Study the Photonic Properties of Disordered Photonic Bandgap Materials
10:35

Using Microwave and Macroscopic Samples of Dielectric Solids to Study the Photonic Properties of Disordered Photonic Bandgap Materials

Published on: September 26, 2014

12.3K
Free-form Light Actuators — Fabrication and Control of Actuation in Microscopic Scale
08:17

Free-form Light Actuators — Fabrication and Control of Actuation in Microscopic Scale

Published on: May 25, 2016

9.3K
Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging
07:14

Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging

Published on: April 11, 2025

627

Area of Science:

  • Photonics and Optics
  • Condensed Matter Physics

Background:

  • Disordered photonic media feature randomly distributed scatterers.
  • Light propagation involves multiple scattering events, akin to a random walk.
  • Micro- and nano-scale structures enhance light-matter interactions.

Purpose of the Study:

  • To discuss the fundamental physics of light propagation in disordered structures.
  • To review the phenomenon of random lasing.
  • To highlight recent advancements and biomedical applications of random lasers.

Main Methods:

  • Theoretical discussion of light propagation and multiple scattering.
  • Review of experimental techniques for random laser fabrication and characterization.
  • Analysis of recent literature on random laser advancements.

Main Results:

  • Random lasing arises from coherent backscattering in disordered media with gain.
  • Tunable, quasi-monochromatic emission is characteristic of random lasers.
  • Disordered structures provide a versatile platform for novel laser functionalities.

Conclusions:

  • Random lasing is a unique phenomenon driven by light scattering in disordered media.
  • Recent progress has expanded the capabilities and applications of random lasers.
  • Future potential lies in biomedical imaging and biosensing.