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Random Lasing for Bimodal Imaging and Detection of Tumor
R Gayathri1, C S Suchand Sandeep1, C Vijayan2
1Centre for Optical and Laser Engineering (COLE), School of Mechanical and Aerospace Engineering, Nanyang Technological University (NTU), Singapore 639798, Singapore.
Biosensors
|December 22, 2023
Summary
Researchers developed a random lasing system for early cancer detection. This technology identifies and images tiny tumor polyps, offering a minimally invasive approach for disease diagnosis.
Area of Science:
- Biomedical Optics
- Photonics
- Cancer Diagnostics
Background:
- Biological tissues scatter light, enabling random lasing emission.
- Random lasing signals contain information about tissue scattering dynamics.
- Early tumor detection is vital for cancer treatment.
Purpose of the Study:
- To propose and demonstrate a bimodal system for tumor identification and imaging.
- To utilize random lasing principles for early cancer diagnosis.
- To develop a non-contact, in vivo inspection method.
Main Methods:
- A bimodal spectroscopic and imaging system was developed.
- Random lasing principles were integrated with sensing and imaging.
- A phantom sample was used to validate the system's capabilities.
Main Results:
- The system successfully identified and imaged tumor polyps as small as 1 mm².
- Far-field imaging enabled non-contact inspection.
- The system demonstrated potential for early tumor growth diagnosis.
Conclusions:
- The developed system offers an efficient, minimally invasive method for early disease detection.
- Integration of random lasing with imaging modalities shows promise for cancer diagnostics.
- This technology can aid in the early detection and treatment of various diseases.
