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Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds.

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Chemically modified cotton fabrics with organoselenium compounds show potent antimicrobial properties. This durable treatment effectively kills bacteria and fungi without disrupting textile production.

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Area of Science:

  • Materials Science
  • Textile Chemistry
  • Antimicrobial Agents

Background:

  • Cotton fabrics are widely used but lack inherent antimicrobial properties.
  • Developing durable antimicrobial textiles is crucial for healthcare and consumer goods.
  • Traditional antimicrobial treatments can be harsh or disrupt manufacturing.

Purpose of the Study:

  • To develop a novel method for imparting antimicrobial properties to cotton fabrics.
  • To investigate the efficacy of organoselenium compounds as antimicrobial agents for textiles.
  • To assess the durability and compatibility of the treatment with existing textile processes.

Main Methods:

  • Cotton fabrics (bleached and cationized) were chemically modified using reactive organoselenium compounds via nucleophilic aromatic substitution (SNAr).
  • Organoselenium attachment was achieved through covalent bonds and ionic interactions (for cationized cotton).
  • Antimicrobial efficacy was tested against *Staphylococcus aureus*, *Escherichia coli*, and *Candida albicans*.

Main Results:

  • Treated fabrics demonstrated potent bactericidal activity against *S. aureus* (99.99% reduction).
  • Moderate activity was observed against *E. coli*, and significant fungicidal activity against *C. albicans*.
  • Antifungal activity was higher on cationized cotton, and the antimicrobial effect was durable to washing.

Conclusions:

  • A novel, durable method for creating antimicrobial cotton fabrics using organoselenium compounds has been developed.
  • This approach offers effective bacterial and fungal resistance without disrupting industrial textile production.
  • The findings present a promising strategy for functionalizing textiles with antimicrobial properties.