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Updated: Jul 16, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

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Morphine induces HADHA succinylation, while HADHA desuccinylation alleviates morphine tolerance by influencing

Yuanxin Huang1, Sihui Lu2, Yu Chen1,3

  • 1Department of Pain, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.

Naunyn-Schmiedeberg'S Archives of Pharmacology
|September 9, 2023
PubMed

Keywords:
AutophagyHADHAMorphine toleranceSIRT5Succinylation

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