Related Experiment Video
Updated: Jul 16, 2025

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
Published on: April 26, 2015
Ketamine during resuscitation - Is it as hemodynamically perfect as we think?
Steven G Schauer1, Michael D April2, Allyson A Arana3
1Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA; Departments of Anesthesiology and Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA; Center for Combat and Battlefield (COMBAT) Research, University of Colorado School of Medicine, Aurora, Colorado, USA.
Ketamine use in trauma patients may not improve oxygen delivery to tissues, despite increasing standard vital signs like blood pressure and heart rate. Further research is needed to understand ketamine
Area of Science:
- Trauma resuscitation
- Anesthesiology
- Critical care medicine
Background:
- Ketamine is often presumed to have a favorable hemodynamic profile for hypotensive patients.
- The Compensatory Reserve Measurement (CRM) algorithm tracks systemic oxygen delivery adequacy (DO2).
Related Concept Videos
Cardiopulmonary Resuscitation IV: Pharmacological Management
Parenteral Anesthetics: Overview

