Opioid stewardship and perioperative management of pediatric tympanoplasty

Rahiq Rahman1, Chhaya Patel2, Campbell Hathaway3

  • 1Children's Healthcare of Atlanta, Atlanta, GA, USA.

Insights

Endoscopic tympanoplasty in children requires fewer opioids and shorter hospital stays than microscopic approaches, with similar success rates for ear drum repair. This minimally invasive technique offers a less painful experience and promotes opioid stewardship.

Area of Science:

  • Otolaryngology
  • Pediatric Surgery
  • Minimally Invasive Surgery

Background:

  • Tympanoplasty is a common surgical procedure to repair eardrum perforations.
  • Microscope-assisted and endoscope-assisted techniques are utilized for tympanoplasty.
  • Comparative data on pediatric outcomes, particularly pain management and admission course, are valuable.

Purpose of the Study:

  • To compare the intraoperative management, admission course, pain management, and graft success of microscope- and endoscope-assisted tympanoplasty in pediatric patients.
  • To evaluate the effectiveness and safety of endoscopic versus microscopic approaches in children undergoing tympanoplasty.

Main Methods:

  • Retrospective chart review of 321 pediatric patients (≤18 years) who underwent ambulatory tympanoplasty between January 2018 and December 2020.
  • Data collected included intraoperative factors, surgical approach, complications, and perforation closure success rates.
  • Multivariate analysis was performed to compare the two surgical approaches.

Main Results:

  • Endoscopic tympanoplasty (17.4%) and microscopic tympanoplasty (82.6%) showed similar rates of intraoperative complications, postoperative complications, audiological improvement, and perforation closure.
  • Patients undergoing endoscopic tympanoplasty were significantly less likely to require postoperative opioids (3.96 times) and had shorter hospital admissions.
  • Graft type (autograft) did not influence opioid requirements.

Conclusions:

  • Both endoscopic and microscopic tympanoplasty are viable surgical options for pediatric patients.
  • Endoscopic tympanoplasty demonstrates a reduced need for postoperative opioids and shorter admissions compared to the microscopic approach, with comparable graft success.
  • The minimally invasive endoscopic approach offers a less painful perioperative experience for children and supports appropriate opioid stewardship.
Abstract

Related Concept Videos

Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
286
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
331
Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
652
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
15
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
134
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
154