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Updated: Jul 16, 2025

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
Published on: March 16, 2018
Opioid stewardship and perioperative management of pediatric tympanoplasty
Rahiq Rahman1, Chhaya Patel2, Campbell Hathaway3
1Children's Healthcare of Atlanta, Atlanta, GA, USA.
Insights
Endoscopic tympanoplasty in children requires fewer opioids and shorter hospital stays than microscopic approaches, with similar success rates for ear drum repair. This minimally invasive technique offers a less painful experience and promotes opioid stewardship.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Minimally Invasive Surgery
Background:
- Tympanoplasty is a common surgical procedure to repair eardrum perforations.
- Microscope-assisted and endoscope-assisted techniques are utilized for tympanoplasty.
- Comparative data on pediatric outcomes, particularly pain management and admission course, are valuable.
Purpose of the Study:
- To compare the intraoperative management, admission course, pain management, and graft success of microscope- and endoscope-assisted tympanoplasty in pediatric patients.
- To evaluate the effectiveness and safety of endoscopic versus microscopic approaches in children undergoing tympanoplasty.
Main Methods:
- Retrospective chart review of 321 pediatric patients (≤18 years) who underwent ambulatory tympanoplasty between January 2018 and December 2020.
- Data collected included intraoperative factors, surgical approach, complications, and perforation closure success rates.
- Multivariate analysis was performed to compare the two surgical approaches.
Main Results:
- Endoscopic tympanoplasty (17.4%) and microscopic tympanoplasty (82.6%) showed similar rates of intraoperative complications, postoperative complications, audiological improvement, and perforation closure.
- Patients undergoing endoscopic tympanoplasty were significantly less likely to require postoperative opioids (3.96 times) and had shorter hospital admissions.
- Graft type (autograft) did not influence opioid requirements.
Conclusions:
- Both endoscopic and microscopic tympanoplasty are viable surgical options for pediatric patients.
- Endoscopic tympanoplasty demonstrates a reduced need for postoperative opioids and shorter admissions compared to the microscopic approach, with comparable graft success.
- The minimally invasive endoscopic approach offers a less painful perioperative experience for children and supports appropriate opioid stewardship.
Objective:
To provide insight into the intraoperative management, admission course, pain management, and graft success of microscope- and endoscope-assisted tympanoplasty.
Study Design:
Retrospective Chart Review.
Methods:
This study included children 18 years and younger who underwent ambulatory tympanoplasty at a tertiary pediatric hospital between January 2018 and December 2020. Medical records were reviewed and information about intraoperative factors, surgical approach, laterality, complications, and post-operative perforation closure success rates was collected. Multivariate analysis was performed to compare and contrast the two surgical approaches.
Results:
The review included 321 pediatric patients who underwent a tympanoplasty. Endoscopic tympanoplasty accounted for 17.4%, while microscopic tympanoplasty accounted for 82.6%. In both approaches, the rate of intraoperative complications, postoperative complications, audiological improvements, and perforation closure success rates were statistically similar. However, patients who underwent endoscopic tympanoplasty were 3.96 times less likely to require opioids in the post-anesthesia care unit (PACU) and had a shorter post-operative admission length. This pattern emerged regardless of the type of graft used. Obtaining an autograft was not associated with a higher opioid requirement in the PACU.
Conclusion:
While both approaches are viable, our findings demonstrate the reduced need for opioids with similar success rates following an endoscopic tympanoplasty. Ultimately, the trade-off for the minimally invasive endoscopic approach appears to be a less painful experience for the child while promoting clinically appropriate opioid stewardship in the perioperative setting.
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