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[Primary retroperitoneal tumors].

A Frilling, K Grabitz, H Nier

    Deutsche Medizinische Wochenschrift (1946)
    |October 24, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Primary retroperitoneal tumors are rare and often present with atypical symptoms. Complete surgical removal is challenging, and the overall prognosis remains poor, highlighting the need for multimodal treatment approaches.

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    Area of Science:

    • Oncology
    • Surgical Pathology
    • Diagnostic Imaging

    Context:

    • Retrospective analysis of 73 patients treated for primary retroperitoneal tumors between 1974 and 1984.
    • Mean patient age was 45.9 years, with a wide range from 1 day to 79 years.
    • Tumors presented with atypical early symptoms, often diagnosed as palpable abdominal masses.

    Purpose:

    • To evaluate the diagnostic methods, surgical management, and outcomes of primary retroperitoneal tumors.
    • To assess the prognostic factors and survival rates associated with these rare malignancies.
    • To review the role of computed tomography in diagnosing retroperitoneal tumors.

    Summary:

    • Computed tomography (CT) is identified as the crucial radiologic tool for diagnosis.
    • Complete tumor removal was achieved in 32 patients, frequently requiring resection of adjacent organs.

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  • Histological analysis revealed lymphomas and sarcomas as the most common types; 21 patients had metastases at diagnosis.
  • The operative mortality rate was 11%.

    • Impact:

    • The study underscores the poor overall prognosis for primary retroperitoneal tumors, with a 5-year survival rate of 9% for malignant cases.
    • Aggressive surgical resection, including adjacent organ removal, is necessary for radical extirpation.
    • Recent advancements in combined radio- and chemotherapy offer potential for improving the grim prognosis.