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Adversarial attacks in radiology - A systematic review.

Vera Sorin1, Shelly Soffer2, Benjamin S Glicksberg3

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Adversarial attacks on deep learning in radiology are a growing cybersecurity concern. While currently theoretical, these attacks pose a risk, necessitating enhanced security and ethical guidelines for safe AI implementation.

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Area of Science:

  • Medical Imaging and Artificial Intelligence
  • Cybersecurity in Healthcare
  • Deep Learning Applications in Radiology

Background:

  • Deep learning is increasingly used in radiology, raising cybersecurity concerns, especially regarding adversarial attacks.
  • Adversarial attacks can manipulate AI models, potentially impacting diagnostic accuracy and patient safety.
  • A systematic review is needed to understand the landscape of adversarial attacks in the field.

Approach:

  • A systematic literature search was conducted using MEDLINE and Google Scholar up to April 2023.
  • The review included 22 studies published between March 2018 and April 2023.
  • Studies focused on adversarial attacks against various radiological image classification algorithms.

Key Points:

  • Most studies (14/22) evaluated white-box attacks, with some achieving 100% success rates and reducing algorithm performance (AUC) to 0.
  • Chest X-ray classification algorithms were the most frequent targets (11/22), followed by chest CT, brain MRI, and mammography.
  • Attacks demonstrated significant potential to compromise the integrity of deep learning models in radiology.

Conclusions:

  • Adversarial attacks represent a significant, albeit currently theoretical, risk to the safe deployment of deep learning in radiology.
  • Proactive measures, including strengthened cybersecurity protocols and the development of ethical and legal frameworks, are crucial.
  • Ensuring the secure and reliable use of AI in medical imaging requires ongoing vigilance and adaptation.