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Updated: Jul 14, 2026

Necropsy-based Wild Fish Health Assessment
Published on: September 11, 2018
[Ecological Toxic Effect of Perfluorinated Compounds on Fish Based on Meta-analysis].
Hong Lu1,2, Jin-Yang Zhou1,2, Fan Yang1,2
1School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Per- and polyfluoroalkyl substances (PFAS) pose significant risks to fish, impacting seven key functional traits, with malformations being the most severe. Aquatic toxicity varies by fish sex and life stage, with female embryos being most vulnerable.
Area of Science:
- Environmental toxicology
- Aquatic ecotoxicology
- Chemical risk assessment
Background:
- Per- and polyfluoroalkyl substances (PFAS) are persistent, bioaccumulative, and toxic organic pollutants.
- Their widespread presence in aquatic ecosystems raises concerns about ecological impacts.
- Understanding PFAS toxicity in fish is crucial for environmental management.
Conclusions:
- PFAS significantly impact multiple functional traits in fish, with malformations being a primary concern.
- Fish sex and developmental stage, particularly embryos, are critical factors influencing PFAS susceptibility.
- Specific PFAS chemical structures and exposure concentrations dictate the severity of toxicological outcomes.
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