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Related Concept Videos

Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
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Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

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Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
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Primary Lymphoid Organs01:16

Primary Lymphoid Organs

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Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
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Updated: Jul 16, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
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Leukemic-phase mucosa-associated lymphoid tissue lymphoma.

Takayuki Yotsuyanagi1, Naoto Tomita2, Yusuke Saiki1

  • 1Hematology and Oncology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.

International Journal of Hematology
|September 12, 2023
PubMed
Summary

This case report details a rare instance of leukemic-phase mucosa-associated lymphoid tissue (MALT) lymphoma in a 78-year-old man. Diagnosis involved flow cytometry, imaging, and molecular analysis confirming widespread MALT lymphoma.

Area of Science:

  • Hematology
  • Oncology
  • Immunology

Background:

  • Leukemic-phase mucosa-associated lymphoid tissue (MALT) lymphoma is an exceptionally rare hematologic malignancy.
  • MALT lymphomas typically arise in extranodal sites, and their presentation in the leukemic phase is uncommon.
Keywords:
IgH rearrangementLeukemic stateMALT lymphomaOrbit

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