Association of leadless pacing with ventricular and valvular function
Kelly Arps1, Bicong Li1, John Carson Allen1
1Division of Cardiovascular Disease, Section of Cardiac Electrophysiology, Duke University Medical Center, Durham, North Carolina, USA.
Journal of Cardiovascular Electrophysiology
|September 13, 2023
Summary
Leadless pacemakers did not worsen tricuspid regurgitation but were associated with reduced biventricular function. This study assessed leadless pacing effects on valvular and ventricular function.
Area of Science:
- Cardiology
- Medical Devices
- Electrophysiology
Background:
- Transvenous pacemakers can impair tricuspid valve function and cause ventricular dysfunction due to lead impingement and right ventricular (RV) pacing.
- The impact of leadless pacing on valvular and ventricular function remains less understood.
Purpose of the Study:
- To evaluate the association between leadless pacemaker implantation and changes in valvular regurgitation and ventricular function.
Main Methods:
- Echocardiographic data from 54 patients before and after leadless pacemaker implantation were analyzed.
- Valvular regurgitation was graded, and left ventricular ejection fraction (LVEF) and tricuspid annular plane systolic excursion (TAPSE) were measured.
Main Results:
- No significant change in tricuspid regurgitation severity was observed post-implant.
- A decrease in average LVEF (52.3% to 47.9%) and TAPSE (1.8 to 1.6) was noted.
- Twenty-four percent of patients experienced an absolute LVEF drop of ≥10%.
Conclusions:
- Leadless pacing did not lead to short-term worsening of valvular function.
- Consistent with RV pacing effects, leadless pacing was linked to diminished biventricular function.
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