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Published on: November 8, 2018
Refractory seizures in a dialysis patient and a vitamin consigned to oblivion
Satish Haridasan1, Rakesh Madhyastha1, Muriel Ghosn1
1Medical Sub-specialties Institute, Department of Nephrology.
Abstract:
Intradialytic breakthrough seizures refractory to multiple classes of antiepileptic medications are not common and can be due to many different reasons. Pyridoxine deficiency is an under-recognized cause of such seizures and frequently missed in clinical practice. Many factors specifically related to dialysis can lead to pyridoxine deficiency and in turn can contribute to refractory seizures. Herein, we report one of the very few cases of intradialytic breakthrough refractory seizures secondary to pyridoxine deficiency recognized in the literature.
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