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Updated: Jul 16, 2025

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Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
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Terahertz biosensor integrated with Au nanoparticles to improve the sensing performance.
Applied Optics
|September 14, 2023
Summary
This study introduces a terahertz (THz) sensor using gold nanoparticles (AuNPs) integrated with a metasurface. The AuNPs significantly boost the sensor
Area of Science:
- Optoelectronics
- Nanotechnology
- Biomedical Sensing
Background:
- Terahertz (THz) biosensors offer label-free detection capabilities.
- Metasurfaces provide a platform for enhancing sensor performance.
- Improving sensitivity in biosensing remains a key challenge.
Purpose of the Study:
- To develop a highly sensitive terahertz (THz) biosensor.
- To investigate the role of gold nanoparticles (AuNPs) in enhancing sensor performance.
- To improve the detection of whey protein using a metasurface-based THz sensor.
Main Methods:
- Fabrication of a metasurface integrated with gold nanoparticles (AuNPs).
- Utilizing terahertz (THz) spectroscopy for sensing applications.
- Applying modified perturbation theory and coupled harmonic oscillator models for mechanism analysis.
Main Results:
- The integrated AuNPs demonstrably improved the sensitivity of the THz sensor.
- Enhanced sensing index of group delay was observed.
- The AuNPs effectively boosted the overall sensing performance of the biosensor.
Conclusions:
- Gold nanoparticles (AuNPs) are effective in enhancing the sensitivity of metasurface-based THz biosensors.
- The study validates the use of AuNPs for improved whey protein detection.
- This work presents a viable strategy for advancing THz biosensing technology.

