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Updated: Jul 16, 2025

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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published on: September 21, 2017
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Correction: Cyclopentane FIT-PNAs: bright RNA sensors
Odelia Tepper1, Hongchao Zheng2, Daniel H Appella2
1The Institute for Drug Research, The School of Pharmacy, The Hebrew University of Jerusalem, Hadassah Ein-Kerem, Jerusalem 91120, Israel. eylony@ekmd.huji.ac.il.
Summary
This correction clarifies details for cyclopentane-based fluorescent intercalator nucleic acid sensors (FIT-PNAs). These bright RNA sensors offer improved detection capabilities for biological applications.
Area of Science:
- Chemical Biology
- Nucleic Acid Chemistry
- Molecular Sensing
Context:
- Fluorescent intercalator nucleic acid probes are crucial for detecting specific RNA sequences.
- Previous work introduced cyclopentane-based FIT-PNAs as promising RNA sensors.
- Accuracy in reporting experimental details and structural information is vital for reproducibility.
Purpose:
- To correct specific information presented in the original publication 'Cyclopentane FIT-PNAs: bright RNA sensors'.
- To ensure the scientific record accurately reflects the properties and synthesis of these cyclopentane FIT-PNAs.
- To maintain the integrity of research on novel nucleic acid probes.
Summary:
- The correction addresses specific details concerning the synthesis, characterization, or performance of cyclopentane FIT-PNAs.
- It rectifies any inaccuracies in data or interpretations presented in the original communication.
- This ensures the precise understanding of these advanced RNA sensing molecules.
Impact:
- Ensures reliable data for researchers utilizing cyclopentane FIT-PNAs.
- Supports the development of more accurate and sensitive RNA detection tools.
- Upholds the standards of scientific communication and data integrity in chemical communications.

