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Updated: Jul 16, 2025

Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
Refractory generalized myasthenia gravis with myasthenic incomplete ophthalmoplegia successfully treated with
Sara L Weidmayer1,2, Gary Gallagher3
1LTC Charles S. Kettles VA Medical Center, VA Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI, United States.
Purpose:
This is a case of myasthenic incomplete ophthalmoplegia mimicking a partial cranial nerve 3 palsy both subjectively and objectively improving after treatment with eculizumab.
Observations:
We chronicle a case of severe generalized myasthenia gravis including myasthenia masquerading as a partial cranial nerve 3 palsy, refractory to pyridostigmine, mycophenolate, prednisone, intravenous immunoglobulin and plasma exchange but responsive to eculizumab.
Conclusions And Importance:
This case demonstrates ocular and generalized myasthenia gravis refractory to several other therapies but amenable to eculizumab infusions, suggesting this medication may be of significant value in these difficult cases, and should be further explored for refractory ocular myasthenia gravis.
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