Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

External ventricular drain safety campaign and opportunities for global neuroanesthesiology quality and safety.

Current opinion in anaesthesiology·2026
Same author

Exploring the Landscape of Neuroanesthesia Quality Improvement Structure, Processes, and Outcomes: A Pilot Survey.

Journal of neurosurgical anesthesiology·2026
Same author

Ventriculostomy-Related Infections by Country-Income Level: A Systematic Review and Bayesian Hierarchical Meta-analysis.

Journal of neurosurgical anesthesiology·2026
Same author

Association between blood pressure augmentation and brain tissue oxygenation in severe pediatric traumatic brain injury: preliminary findings.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same author

Updated Policy on the Use of Artificial Intelligence for the Journal of Neurosurgical Anesthesiology.

Journal of neurosurgical anesthesiology·2026
Same author

Understanding the practice of neuroanaesthesia across low- and middle-income countries (LMICs): a cross-sectional survey.

Anaesthesia, critical care & pain medicine·2026

Related Experiment Video

Updated: Jul 16, 2025

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
11:26

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression

Published on: December 10, 2014

12.4K

Critical Care Experience With Clinical Cerebral Autoregulation Testing in Adults With Traumatic Brain Injury.

Thitikan Kunapaisal1,2, Monica S Vavilala1, Anne Moore3

  • 1Anesthesiology and Pain Medicine, University of Washington, Seattle, USA.

Cureus
|September 15, 2023
PubMed
Summary

Static cerebral autoregulation testing is safe and feasible for traumatic brain injury (TBI) patients. Results guide individualized care, with impaired autoregulation being common and influencing treatment targets.

Keywords:
adultscerebral autoregulationclinical practicecomplicationsmoderatesafetyseveretbitranscranial dopplertraumatic brain injury

More Related Videos

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
07:12

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

9.3K
A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
06:18

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury

Published on: March 26, 2019

9.0K

Related Experiment Videos

Last Updated: Jul 16, 2025

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
11:26

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression

Published on: December 10, 2014

12.4K
Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
07:12

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

9.3K
A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
06:18

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury

Published on: March 26, 2019

9.0K

Area of Science:

  • Neuroscience
  • Critical Care Medicine
  • Neurology

Background:

  • Traumatic brain injury (TBI) poses significant challenges in critical care.
  • Cerebral autoregulation (CA) is crucial for maintaining brain blood flow.
  • Assessing CA in TBI patients is vital for optimizing management.

Purpose of the Study:

  • To evaluate the feasibility, safety, and utility of static cerebral autoregulation testing.
  • To describe the impact of CA testing on clinical decision-making in TBI patients.
  • To determine the prevalence of impaired CA in this population.

Main Methods:

  • Retrospective review of static CA testing using transcranial Doppler (TCD) ultrasound.
  • Inclusion of adult patients (>18 years) with TBI diagnoses.
  • Analysis of adverse events, autoregulatory index (ARI) values, and changes in intracranial pressure (ICP) and cerebral perfusion pressure (CPP) targets.

Main Results:

  • 135 patients underwent 309 CA tests; 17.8% were not completed due to transient adverse events.
  • 51% of initial tests revealed impaired or absent cerebral autoregulation.
  • CA testing results influenced repeat testing, ICP/CPP targets, and procedural decisions, including decompressive craniectomy.

Conclusions:

  • Static CA testing is feasible and safe in critically injured TBI adults.
  • Testing provides valuable data for individualizing patient care and guiding treatment strategies.
  • Impaired cerebral autoregulation is a frequent finding in moderate-to-severe TBI.