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Radiotherapy and radiosurgery for meningiomas
William C Chen1, Calixto-Hope G Lucas2, Stephen T Magill3
1Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94143, USA.
Neuro-Oncology Advances
|September 15, 2023
Summary
Meningiomas are diverse brain tumors. Current treatments focus on surgery and radiation, as effective systemic therapies are still under development.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Radiation Oncology
Background:
- Meningiomas are common central nervous system tumors with diverse histology and clinical behavior.
- Recent advances have improved understanding of meningioma biology.
- Effective systemic or molecular therapies for meningiomas are still lacking.
Purpose of the Study:
- To review the history, clinical rationale, and future directions of radiotherapy and radiosurgery for meningiomas.
Main Methods:
- Literature review of radiotherapy and radiosurgery for meningiomas.
- Analysis of historical data and current clinical practices.
- Discussion of ongoing preclinical and clinical investigations.
Main Results:
- Maximal safe resection, radiotherapy, and radiosurgery remain the standard treatment modalities for meningiomas.
- Radiotherapy and radiosurgery are integral and effective treatment options.
- Ongoing research aims to develop novel systemic and molecular therapies.
Conclusions:
- Radiotherapy and radiosurgery are established and effective treatments for meningiomas.
- Further research is needed to develop targeted therapies.
- A multidisciplinary approach is crucial for optimal meningioma management.
