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Updated: Jul 16, 2025

Quantification of Reactive Oxygen Species Using 2′,7′-Dichlorofluorescein Diacetate Probe and Flow-Cytometry in Müller Glial Cells
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NRF2 signalling in cytoprotection and metabolism

Shohei Murakami1, Yusuke Kusano1,2, Keito Okazaki1

  • 1Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.

British Journal of Pharmacology
|September 16, 2023
PubMed
Summary

The KEAP1-NRF2 system protects cells from oxidative stress. This review explores how NRF2 regulates cellular metabolism, mitochondrial function, and sulfur metabolism, highlighting its cytoprotective roles.

Keywords:
antioxidantmetabolismmitochondriasupersulfide

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