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Evaluation of Willis Polygon Morphometry with Cranial Tomographic Angiography

Rukiye Ciftci1, Aymelek Cetin, Hilal Er Ulubaba

  • 1Bandirma Onyedi Eylul University, Faculty of Medicine, Department of Anatomy, Balıkesir, Turkey.

Turkish Neurosurgery
|September 16, 2023
PubMed

Insights

Vessel diameters in the Willis polygon were smaller in patients with type 2 diabetes mellitus (T2DM) and hypertension (HT) compared to healthy individuals. These morphometric differences in T2DM and HT patients may inform anatomical evaluations and surgical treatments.

Area of Science:

  • Neuroimaging and vascular anatomy
  • Endocrinology and cardiovascular health

Background:

  • The Circle of Willis (WP) is crucial for cerebral blood supply.
  • Type 2 diabetes mellitus (T2DM) and hypertension (HT) are significant risk factors for cerebrovascular diseases.
  • Understanding WP morphometry in these conditions is vital for clinical practice.

Purpose of the Study:

  • To investigate the morphometric properties of the Willis polygon vessels.
  • To compare these properties between patients with T2DM, HT, combined T2DM and HT, and healthy controls.

Main Methods:

  • Retrospective analysis of 168 Cranial Tomography Angiographies (CTA).
  • Patients categorized into four groups: HT, DM, HT+DM, and healthy controls.
  • Measurements of diameter and length of WP vessels.

Main Results:

  • Statistically significant differences in vessel diameters were observed between groups, particularly in females.
  • Specific segments of the anterior cerebral artery (ACA), posterior cerebral artery (ACP), and anterior communicating artery (AComP) showed variations.
  • Vessel diameters were consistently smaller in the HT, DM, and HT+DM groups compared to the control group.

Conclusions:

  • Morphometric variations in the Willis polygon are associated with T2DM and HT.
  • The observed smaller vessel diameters in patients with T2DM and/or HT compared to controls highlight potential vascular adaptations or pathologies.
  • Knowledge of WP morphometrics aids radio-anatomical assessments and enhances microanatomical understanding for surgical interventions.
Abstract

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