Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic non-hematogenous osteomyelitis treated with adjuvant hyperbaric oxygen.

J C Davis, J D Heckman, J C DeLee

    The Journal of Bone and Joint Surgery. American Volume
    |October 1, 1986
    PubMed
    Summary

    This study found that combining surgery, antibiotics, and hyperbaric oxygen therapy effectively treated chronic osteomyelitis. Most patients remained infection-free for over two years, showing prolonged relief from this bone infection.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A Cadaveric Study on the Variations in the Infraclavicular Part of Brachial Plexus in Axillary Region and Upper Arm.

    BioMed research international·2025
    Same author

    Delayed hypertensive crisis after intracavernosal phenylephrine for penile plication.

    Anaesthesia reports·2025
    Same author

    Double Vagina.

    The Chicago medical journal·2023
    Same author

    Risk factors for recurrent falls in older adults: A systematic review with meta-analysis.

    Maturitas·2020
    Same author

    Searches for Sterile Neutrinos with the IceCube Detector.

    Physical review letters·2016
    Same author

    Decompression Sickness in Sport Scuba Diving.

    The Physician and sportsmedicine·2016

    Area of Science:

    • Orthopedics
    • Infectious Diseases
    • Hyperbaric Medicine

    Background:

    • Chronic non-hematogenous osteomyelitis presents a significant challenge in treatment.
    • Recurrence of infection is common, leading to prolonged patient suffering.
    • Established treatment protocols often have limited long-term success rates.

    Observation:

    • A cohort of 38 patients with chronic non-hematogenous osteomyelitis was treated between 1979 and 1982.
    • Treatment involved local débridements, prolonged parenteral antibiotics, and hyperbaric oxygen therapy (HBOT).

    Findings:

    • 34 out of 38 patients (89.5%) remained free of osteomyelitis signs for an average of 34 months post-treatment.
    • This contrasts with only 4 patients achieving similar outcomes in the preceding two years.

    Related Experiment Videos

  • Treatment failures were observed within one month for three of the four non-responding patients.

    • Implications:

    • This combined therapeutic approach appears to significantly prolong the infection-free interval in chronic osteomyelitis.
    • Hyperbaric oxygen therapy, as an adjunct, shows promise in managing refractory osteomyelitis.
    • Further research into optimizing HBOT protocols for osteomyelitis is warranted.