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Updated: Jul 16, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
New formulation technology to boost sun protection
Hélène Meaudre1, Odile Aubrun1, Jean-Baptiste Boitte1
1L'Oréal R&I, Chevilly-Larue, France.
Objective:
As every skin type worldwide is concerned by photoprotection, with consumers preferring cosmetic elegant and efficient sunscreen products, we aim at developing the most performant and desirable sun care products.
Methods:
We selected an interesting polymer, abbreviated AAHCP and designed scanning electron cryomicroscopy (cryoSEM), small angle and wide angle X-ray scattering and confocal laser scanning microscopy studies to understand its behaviour in solution and in simplex sun care formulations. This allowed us to develop innovative sunscreen formulation technology that was demonstrated by in vitro and in vivo photoprotection methods. Comprehensive photoprotection evaluations were made on the fully developed sun protection product.
Results:
We observed the polymer oil structuring properties as well as its ability to form small and stable droplets in simplex emulsions. In vitro and in vivo sun protection factor (SPF) measurements demonstrated the sun protection boosting efficacy of AAHCP polymer in several emulsions or as a stand-alone emulsifier. This formulation technology also allowed to filtering system concentration optimization. Use-test performed on a fully developed AAHCP-based sunscreen validated its optimal performances as well as its ideal cosmetic features, with non-sticky, non-greasy perception and invisible skin result.
Conclusion:
For the first time, thanks to a new specific polymer creating a new type of emulsion, we succeed in reconciliate in a single sun care product maximal SPF efficacy, resistance to numerous stresses and optimal sensoriality.
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