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Updated: Jul 16, 2025

Generating Transgenics and Knockouts in Strongyloides Species by Microinjection
Published on: October 7, 2021
Strongyloides stercoralis Hyperinfection Syndrome in Pregnancy
Allison N Akers1, Adriana Vest1, Claudio V Schenone1
1Obstetrics and Gynecology, University of South Florida, Tampa, USA.
Abstract:
Strongyloidiasis is a parasitic infection with a high global burden of disease. Hyperinfection syndrome is a life-threatening complication that predominantly affects immunosuppressed individuals, such as those receiving corticosteroid treatment. Despite its worldwide prevalence, little is known about the clinical effects of this condition on the feto-maternal dyad during pregnancy. We present a case of placental abruption leading to preterm delivery in a pregnancy complicated by Strongyloides stercoralis hyperinfection syndrome following antenatal corticosteroid use. Although rare, this condition is associated with high mortality rates and adverse pregnancy outcomes. Therefore, screening at-risk individuals may be warranted in pregnancies where antenatal corticosteroid administration is considered.
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