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Updated: Jul 16, 2025

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
Published on: February 9, 2021
Climate change and kidney stones
Grace E Maline1, David S Goldfarb1,2
1NYU Grossman School of Medicine.
Rising global temperatures and urbanization are increasing kidney stone incidence. This trend exacerbates health disparities, necessitating strategies to mitigate heat exposure risks for kidney health.
Area of Science:
- Environmental Health
- Nephrology
- Climate Science
Background:
- Kidney stones represent a growing public health concern with significant economic and quality-of-life impacts.
- Increasing global surface temperatures due to climate change and urbanization are identified as key drivers of kidney stone prevalence.
- Urban heat islands (UHIs) may intensify heat exposure, disproportionately affecting vulnerable populations and exacerbating existing health disparities.
Approach:
- This review synthesizes current research on the relationship between heat exposure and kidney stone formation.
- It examines how climate change and urbanization contribute to increased risk.
- The review also addresses the social and environmental factors influencing kidney stone epidemiology.
Key Points:
- High temperatures directly increase the risk of kidney stone development.
- Vulnerability to heat effects varies by sex, comorbidities, and population adaptability.
- Urban heat islands (UHIs) amplify temperature extremes, with potential links to historical redlining and health disparities in the U.S.
Conclusions:
- Continued increases in global temperatures and urbanization will likely lead to a higher prevalence of kidney stones.
- Climate change impacts on kidney stone disease may perpetuate social inequalities in kidney health.
- Developing strategies to mitigate heat exposure is crucial for preventing kidney stones and addressing health disparities.
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