Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Network Covalent Solids02:18

Network Covalent Solids

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Circuit Terminology01:14

Circuit Terminology

An electrical network is a system composed of interconnected elements, such as resistors, capacitors, inductors, and voltage or current sources. Unlike a circuit, an electrical network does not necessarily form a closed path. In other words, while all circuits can be considered networks due to their interconnected nature, not every network qualifies as a circuit.
A circuit, on the other hand, is also an interconnected system of electrical elements but must contain one or more closed paths.
Network Function of a Circuit01:25

Network Function of a Circuit

Frequency response analysis in electrical circuits provides vital insights into a circuit's behavior as the frequency of the input signal changes. The transfer function, a mathematical tool, is instrumental in understanding this behavior. It defines the relationship between phasor output and input and comes in four types: voltage gain, current gain, transfer impedance, and transfer admittance. The critical components of the transfer function are the poles and zeros.
Block Diagram Reduction01:22

Block Diagram Reduction

The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of Colombian silk fibroin hydrogels functionalized with recombinant LSECtin for intervertebral disc tissue engineering.

PloS one·2026
Same author

Engineering tough blood clots for rapid haemostasis and enhanced regeneration.

Nature·2026
Same author

Development and validation of an osteoporosis risk-assessment model for Chinese older adults: a large-scale retrospective study.

BMC geriatrics·2026
Same author

Enhancing Membrane Adhesion to Polymeric Substrates via Plasma Treatment.

ACS applied polymer materials·2026
Same author

A Continuum Robotic Bioprinter for <i>in situ</i> Vocal Fold Repair.

Device·2026
Same author

Agitation-Driven Fusion Fabrication of Macroscopic Cell-Laden Cryogels.

ACS applied bio materials·2026
Same journal

Tau protein as a regulator of mitochondrial function and dynamics.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

A scalable, dividing cell model for the robust propagation and quantification of human sporadic Creutzfeldt-Jakob disease prions.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Epigenetic regulation of mesenchymal BMP signaling directs postnatal organ innervation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Single-shot wide-field biochemical imaging at 1 kHz frame rate.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Morphogenesis and topological evolution of a frustrated nematic liquid crystal under confinement.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

B cell-intrinsic CXCR3 drives efficient generation of ectopic pulmonary germinal center responses to influenza A virus infection.

Proceedings of the National Academy of Sciences of the United States of America·2026
See all related articles

Related Experiment Video

Updated: Jun 29, 2026

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications
08:50

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications

Published on: August 4, 2017

6.8K

Programming hydrogel adhesion with engineered polymer network topology.

Zhen Yang1, Guangyu Bao1, Ran Huo1

  • 1Mechanical Engineering, McGill University, Montreal, QC H3A 0C3, Canada.

Proceedings of the National Academy of Sciences of the United States of America
|September 19, 2023
PubMed
Summary
This summary is machine-generated.

Researchers developed a universal strategy for programmable hydrogel adhesion by engineering surface network topology. This allows tunable adhesion in magnitude, space, and time for advanced applications like tissue engineering and soft robotics.

Keywords:
controlled adhesionhydrogel adhesivespolymer entanglementpolymer gels

More Related Videos

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

7.2K
Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.5K

Related Experiment Videos

Last Updated: Jun 29, 2026

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications
08:50

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications

Published on: August 4, 2017

6.8K
An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
08:17

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

7.2K
Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.5K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Biomaterials Engineering

Background:

  • Tunable hydrogel adhesion is crucial for advanced applications but challenging to achieve.
  • Current methods often integrate complex mechanisms, hindering practical use.

Purpose of the Study:

  • To develop a universal strategy for multifaceted adhesion programmability in synthetic hydrogels.
  • To enable dynamic control over adhesion magnitude, space, and time within a single hydrogel system.

Main Methods:

  • Engineering the surface network topology of hydrogels to form supramolecular linkages.
  • Investigating polymer chain slippage, rupture, and diffusion to understand adhesion mechanisms.
  • Fabricating various soft devices utilizing the programmable adhesion properties.

Main Results:

  • Achieved dynamically tunable adhesion with high-resolution spatial programmability.
  • Demonstrated stable and tunable adhesion kinetics independent of bulk mechanics and chemistry.
  • Successfully designed and fabricated smart wound patches, fluidic channels, drug-eluting devices, and reconfigurable soft robotics.

Conclusions:

  • Presents a simple and robust platform for integrating multifaceted adhesion controllability into hydrogel design.
  • Enables tailored adhesion properties for diverse applications in tissue engineering, soft robotics, and wearable devices.
  • Advances the development of next-generation smart materials and soft devices.