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Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids
G I Butel-Simoes1, H Kua2, A Safdar3
1Monash Infectious Diseases and Microbiology, Monash Health, Victoria, Australia.
Abstract:
We present a case of laryngeal cryptococcosis caused by cryptococcosis neoformans var. grubii affecting a patient using excessive inhaled corticosteroids. The patient experienced symptoms for several months prior to specialist review and the visualization of a mass lesion by nasopharyngoscopy. Fortunately a biopsy was performed and through histopathology & microbiological assessment a diagnosis of cryptococcal laryngitis was made. Treatment with 6 months of fluconazole resulted in clinical cure and resolution of symptoms. It is important to raise awareness of the risk of non-Candida fungal infections in patients on high dose corticosteroids, especially in the post covid era were steroids are more commonly prescribed.
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