Danazol therapy for proximal obstruction of the oviduct

Danazol therapy for proximal tubal obstruction and associated endometriosis has been suggested to be highly effective. Of 12 women treated with danazol for two to nine months, 5 had resolution of their proximal tubal obstruction after three to eight months of therapy. Two of the five had no associated pelvic endometriosis, and one of them became pregnant. Due to the heterogeneity of the patient population studied, it is difficult to make a definitive statement about the efficacy of danazol in patients with proximal tubal obstruction. However, the data suggest that danazol is effective in the treatment of some patients with proximal tubal obstruction and should be considered prior to surgery.