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Regulatory Light-Chain Phosphorylation During Weightlifting Training: Association With Postactivation Performance

Loren Z F Chiu1, Andrew C Fry2, Andrew J Galpin3

  • 1Neuromusculoskeletal Mechanics Research Program, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.

Journal of Strength and Conditioning Research
|September 20, 2023
PubMed
Summary
This summary is machine-generated.

Regulatory light-chain (RLC) phosphorylation may initially enhance weightlifting performance during repeated sets. This study found RLC phosphorylation was associated with improved average barbell power in male athletes during training.

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Area of Science:

  • Exercise Physiology
  • Muscle Physiology

Background:

  • Postactivation performance enhancement (PAPE) in resistance exercise is attributed to neural and intrinsic muscle factors.
  • Understanding the molecular mechanisms behind PAPE is crucial for optimizing training protocols.

Purpose of the Study:

  • To investigate the association between regulatory light-chain (RLC) phosphorylation and enhanced weightlifting performance.
  • To determine if RLC phosphorylation in primary movers correlates with performance improvements during a multijoint exercise.

Main Methods:

  • Nine male athletes performed 15 sets of 3 repetitions of clean pulls at 85% of their 1 repetition maximum.
  • Performance metrics including peak barbell velocity (PV) and average barbell power (AP) were measured via video analysis.
  • Vastus lateralis muscle biopsies were collected pre- (PRE), mid- (MID), and post- (POST) training to assess RLC phosphorylation.

Main Results:

  • Average barbell power (AP) significantly increased from set 1 to sets 3, 4, and 5 (large effect sizes).
  • Increases in peak barbell velocity (PV) were not significant but showed moderate effect sizes for sets 3 and 4.
  • Relative changes in AP and RLC phosphorylation were positively correlated at MID (r = 0.60) and negatively correlated at POST (r = -0.74).

Conclusions:

  • RLC phosphorylation may play an initial role in postactivation performance enhancement during repeated bouts of multijoint weightlifting exercise.
  • These findings suggest a potential molecular link between RLC phosphorylation and acute performance gains in strength training.